Bacteriological Resistance Against Antibiotics

Time for a new resistance against antibiotics

Resistance of pathogenic organisms to antimicrobial agents can seem far from a clinician’s mind during everyday consultations with patients. A recent systematic review of clinicians’ views about antimicrobial resistance reported that they believed that antimicrobial resistance was a serious (but distant) problem that was mainly caused by patients’ incomplete adherence to prescriptions or self-m...

Synthesis of biofilm resistance characteristics against antibiotics

A phenomenological model for the biofilm resistance against biocide activity is analyzed in this work. The effect of different biofilm physical attributes when exposed to antibiotic treatment is investigated. Pertinent aspects affecting the biofilm resistance characteristics such as transport of the bulk fluid within the reactor, diffusive-reactive transport of the dissolved phase into the biof...

Bacteriological profiling of diphenylureas as a novel class of antibiotics against methicillin-resistant Staphylococcus aureus

Bacterial resistance to antibiotics remains an imposing global public health challenge. Of the most serious pathogens, methicillin-resistant Staphylococcus aureus (MRSA) is problematic given strains have emerged that exhibit resistance to several antibiotic classes including β-lactams and agents of last resort such as vancomycin. New antibacterial agents composed of unique chemical scaffolds ar...

Bacteriological studies on the combined action of aminoglycoside antibiotics and synthetic penicillins against Pseudomonas aeruginosa.

Antibiotics and antibiotic resistance: a bitter fight against evolution.

One of the most terrible consequences of Darwinian evolution is arguably the emergence and spread of antibiotic resistance, which is becoming a serious menace to modern societies. While spontaneous mutation, recombination and horizontal gene transfer are recognized as the main causes of this notorious phenomenon; recent research has raised awareness that sub-lethal concentrations of antibiotics...